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https://www.selleckchem.com/products/apr-246-prima-1met.html Head and neck cancer is increasing globally owing to rising rates of tobacco use and human papillomavirus infection. Today, cancer is the leading cause of death and disabilities in developed countries and the second leading cause of death in countries with developing economies. Understanding the global landscape of head and neck cancer will empower oral and maxillofacial surgeons to play a critical role among patients and societal education regarding the importance of addressing modifiable risk factors and continuing to play an important role in the diagnosis and management of head and neck cancer.Addressing access to oral health care in many low- to middle-income countries is a complicated issue. Oral and maxillofacial surgeons may help engage with vulnerable populations through carefully planned dentoalveolar mission trips. The process of planning a mission includes selecting a population and identifying their unique needs, designing clinic layouts and workflows, team preparation, collection of supplies, fundraising, and advertising. During the mission, methods for protecting privacy, delivering treatment that is standard of care, and sanitation/sterilization options are reviewed. Ethical considerations include avoiding exploitation of vulnerable populations, offending local hosts, need for data collection, and long-term mission sustainability.To prepare global surgeons, academic institutions have created training programs that provide opportunities to develop foundational clinical knowledge, pursue academic inquiry, build surgical infrastructure and capacity, and become advocates and collaborators in resource-limited settings. Academic institutions can create a short course in global surgery, global surgery rotation, global surgery fellowship, or integrated global surgery residency. Global surgery training programs must account for ethics of global surgery engagement, sources of funding, structures for

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