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https://www.selleckchem.com/products/tyloxapol.html Hot flashes are a primary reason for medical visits during menopause. They can interfere with sleep, cause mood disturbances, decrease the overall quality of life, and are associated with significant health care and societal costs. This case report examines the safety and effectiveness of Lepidium peruvianum (maca) for the management of menopausal-related symptoms. A 32-year-old White female presented with hot flashes, night sweats, anxiety, and mood changes following a hysterectomy and oophorectomy. She was provided with a personalized nutrition plan, Lepidium peruvianum (maca), targeted nutrient supplementation, and lifestyle recommendations. These interventions resulted in the safe and effective resolution of hot flashes and anxiety in 2 months and significantly improved her moods and sleep. This case report demonstrated that the use of Lepidium peruvianum, in conjunction with dietary and targeted supplement modifications, appeared to be safe and resulted in the rapid improvements and resolution of symptoms associated with menopause. Long non-coding RNAs (lncRNAs) have been reported to play important roles in the progression of human cancers. Herein, bioinformatic analysis identified that LINC00942 was a highly overexpressed lncRNA in lung adenocarcinoma (LUAD). The present study aimed to explore the roles and possible molecular mechanisms of LINC00942 in LUAD. First, on the basis of TCGA database, the expression and prognosis of LINC00942 were analyzed in LUAD tissues. Then, si-LINC00942 was transfected into A549 and H1299 cells to knockdown the expression of LINC00942. Cell viability was detected by MTT assay. Flow cytometry was used to analyze cell apoptosis. The expressions of PCNA, Bax, Bcl-2, and wnt/β-catenin pathway proteins were detected by western blotting. Dual-luciferase reporter assay was used to evaluate the regulatory relationship between LINC00942 and miR-5006-5p, or miR-5006-5p and FZD1. We disc

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