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https://www.selleckchem.com/products/dexketoprofen-trometamol.html Endobronchial ultrasound (EBUS) guided intranodal forceps biopsy (IFB) is considered complimentary to EBUS-TBNA for patients with intrathoracic lymphadenopathy when either additional tissue is requested for comprehensive molecular testing, or for suspected lymphoma and sarcoidosis. This is a systematic review and meta-analysis to investigate the diagnostic yield and complications of combined EBUS-IFB and EBUS-TBNA compared to EBUS-TBNA alone. We performed a systematic search of MEDLINE, Embase, and Google Scholar for studies evaluating the use of EBUS-IFB for diagnosis of intrathoracic adenopathy, assessing the quality of each study using the QUADAS-2 tool. Using inverse-variance weighting, we performed a meta-analysis of diagnostic yield estimations. We also reviewed the complications related to the procedure. Six observational studies with 443 patients undergoing 467 biopsies were included in the final analysis. Meta-analysis yielded a pooled overall diagnostic yield of 67% (312/467) for EBUS-TBNA andr surgical biopsies. A life-threatening complication of coronavirus disease 2019 (COVID-19) is acute respiratory distress syndrome (ARDS) refractory to conventional management. Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is used to support ARDS patients failing conventional management. Scoring systems to predict mortality in VV-ECMO remain unvalidated in COVID-19 ARDS. We describe the largest COVID-19 VV-ECMO single-center experience to date and assess the utility of standard risk calculators. A retrospective review of a prospective database of all COVID-19 VV-ECMO patients, cannulated between March 15 and June 27 , 2020, at a single academic center was performed. Demographic, clinical, and ECMO characteristics were collected. The primary outcome was in hospital mortality; survivor and non-survivor cohorts were compared utilizing univariate and bivariate analyses. Forty COVID-19 ECMO pati

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