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https://www.selleckchem.com/products/tno155.html While atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) commonly coexist, the efficacy of pulmonary vein isolation in the setting of HFpEF is unclear. In a cohort of patients who underwent cryoballoon ablation (CBA) from 2011 to 2016, we calculated the H FPEF risk score, a novel 6-item score (scale 0-9 points) that accurately predicts the probability of HFpEF. We compared characteristics of patients by H FPEF score and evaluated the association of H FPEF score with 12-month recurrence of AF post-procedure. Of patients with available data to calculate the H FPEF score (n=105), the median H FPEF score was 5 (interquartile range 4-6), corresponding to >80% probability of HFpEF. Compared to patients with H FPEF scores ≤4 (n=34), patients with H FPEF scores of 5 and 6 (n=46) and ≥7 (n=25) carried higher rates of hypertension (≤4 21% vs. 5 and 6 63% vs. ≥7 88%, P<0.001) and diabetes (≤4 0% vs. 5 and 6 9% vs. ≥7 32%, P=0.001). The overall 12-month recurrence rate of AF was 21%. There was no association between H FPEF score and recurrence of AF at 12 months (OR per SD increase in log-H FPEF score 0.87, 95% CI 0.54-1.40, P=0.57). Among patients undergoing CBA for AF, median H FPEF scores are elevated, and screening for occult HFpEF may be warranted in this population. There was no association of the H FPEF score and AF recurrence at 12 months, suggesting efficacy of CBA even among patients with high H FPEF scores. Among patients undergoing CBA for AF, median H2FPEF scores are elevated, and screening for occult HFpEF may be warranted in this population. There was no association of the H2FPEF score and AF recurrence at 12 months, suggesting efficacy of CBA even among patients with high H2FPEF scores.Radiofrequency ablation (RFA) is a commonly performed procedure for symptomatic atrial fibrillation (AF). Herein, we describe a case of transient ST elevation during the isolation of right-sided pulm

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