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https://www.selleckchem.com/products/AG-490.html Iatrogenic Cushing's syndrome has very well-known stigmata on physical examination but can pose a diagnostic challenge when it rarely presents radiologically. We present a classic albeit rarely encountered imaging appearance of Iatrogenic Cushing's on 18F-FDG-PET/CT, with diffuse subcutaneous white adipose proliferation and metabolic activation in a 7-year old patient one-month after starting a high dose steroid regimen for lymphoma. There was an extreme shift in the expected FDG biodistribution with dominant localization to the subcutaneous adipose tissue. This metabolic shift led to sub-threshold visceral biodistribution, rendering the scan non-diagnostic with regards to assessment of oncologic response. Aside from detailing the characteristic imaging findings of Iatrogenic Cushing's and its clinical importance, we discuss the physiologic basis of this imaging pattern and the rarer differential diagnosis to consider when this pattern of uptake is encountered on 18F-FDG-PET/CT. The aim of this study is to evaluate the effect of iron oxide particle deposition on follow-up mammograms and MRI examinations of patients who underwent sentinel lymph node detection with iron oxide particles. Two hundred and eighteen patients who had sentinel lymph node biopsy (SLNB) with iron oxide particles were evaluated. Follow-up MRI and mammography were available in 36 and 69 cases respectively. MRI examinations were evaluated for ferromagnetic artifacts that were graded as follows 0=No artifact, 1=Focal area, 2=Segmental and 3=Regional signal void artifact. Mammography artifacts were evaluated for the presence of dense particles. Pearson's chi-square test was used for statistical analyses and P<0.05 was accepted as significant. MRI artifact grading was as follows Grade 0 11 (30.6%), Grade 1 14 (38.9%), Grade 2 3 (8.3%), and Grade 3 8 (22.2%). The grade of artifacts differed across surgery types (P=0.019). Grade 3 artifacts were higher
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