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https://www.selleckchem.com/products/mira-1.html Objective To determine the temporomandibular disorder (TMD) prevalence in female students and to assess its association with oral parafunctions, neck pain, and function. Methods One hundred forty-four participants were included. The severity of TMD was assessed with Fonseca's Anamnestic Index (FAI). The oral parafunctions were self-reported with the Oral Behaviors Checklist (OBC). Neck pain and neck function were recorded with the Core Outcome Measure Index (COMI). The Spearman correlation analysis was used for statistical analysis. Results Seventy participants (48.6%) had mild TMD. All participants had a positive OBC score, which indicated an oral parafunction. A moderate correlation between TMD and oral parafunctions (p less then 0.001) was detected. Discussion TMD is common in female healthcare students, and its presence is associated with oral parafunctions, neck pain, and function. It is recommended to evaluate oral health habits and neck pain and function in females with TMD. Given the controversy regarding the appropriate dose of β-aminopropionitrile for induction of aortic dissection models in rats, the purpose of this study was to explore the most suitable concentration of β-aminopropionitrile to establish a high-incidence and low-mortality aortic dissection model. Eighty three-week-old male Sprague-Dawley rats were equally divided into four groups a control group, a 0.06% β-aminopropionitrile group, a 0.08% β-aminopropionitrile group and a 0.1% β-aminopropionitrile group. Initial experiments were performed on the control group, which was not treated with β-aminopropionitrile (and drank water freely), and the other three groups, which were given different concentrations of β-aminopropionitrile solution daily (0.06%, 0.08% and 0.1%). Subsequently, on the 40th day, osmotic minipumps administering 1 μg/kg per min angiotensin II (Ang II) were implanted subcutaneously into the β-aminopropionitrile groups, while th

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