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https://www.selleckchem.com/products/vx803-m4344.html ictors are present. CONTEXT The decision to request and proceed with euthanasia or physician-assisted dying (PAD) is complex, and predictors of such decisions are heterogeneous with regard to physical health, psychological, and social factors. Local research is therefore needed. OBJECTIVE To examine the interplay of demographic, clinical and psychosocial factors routinely collected by a standardized clinical instrument, the interRAI Resident Assessment Instrument for Palliative Care (interRAI-PC), in people with a prognosis of less than 12 months who wanted to die. METHODS All New Zealanders who had an interRAI-PC in 2018 were included. The outcome variable was the single item 'Wants to die now'. Independent variables included biopsychosocial factors and health index scales generated by interRAI-PC. A binary logistic regression was used to determine the predictive factors of 'Wants to die now' ('Yes' versus 'No'). RESULTS There were 771 individuals included (mean age 76.0 years, SD=11.6; female 50.1%); 9.3% of whom reported 'Yes' to 'Wants to die now', 59.8% 'No', and for 30.9%, the assessor was 'Unable to determine'. The factors with the largest odds ratios were awareness of terminal prognosis (OR=4.8; 95% CI=2.2-10.3), high level of depression (OR=4.6; 95% CI=1.7-12.6), not finding meaning in day-to-day life (OR=3.8; 95% CI=1.8-8.1), and pain (less than severe OR=3.7; 95% CI=1.3-10.4; severe to excruciating OR=3.5; 95% CI=1.1-10.7). CONCLUSION Addressing the significant factors we identified should form part of a multidisciplinary assessment when terminally ill patients express a wish to die, to ensure their physical, psychological and existential needs are adequately met. Chemotherapy causes various side effects, including cognitive impairment, known as 'chemobrain'. In this study, we determined whether a novel acupuncture mode called electroacupuncture trigeminal nerve stimulation plus body acupuncture (EA/TN

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