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https://www.selleckchem.com/products/l-mimosine.html The amount of collagen in the lung of the RS-504393-treated mice was lower compared with that in the PBS-treated mice. These data suggest that CCR2 antagonist RS-504393 may be a therapeutic agent for human scleroderma. © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.BACKGROUND Patellofemoral pain (PFP) patients show increased prevalence of patellar malalignment. Structural and alignment abnormalities of the patellofemoral joint (PFJ) may play a role in development of PFP and patellofemoral osteoarthritis (PFOA). OBJECTIVES Evaluating associations of patellofemoral alignment and femoral geometry with bony and cartilaginous abnormalities in PFP patients and healthy control subjects. METHODS Data from a case-control study were used (64 PFP subjects, 70 control subjects, 57% female, age 23.2 (6.4)). Alignment and femoral geometry measures in the PFJ were determined using MRI. Structural abnormalities in the PFJ associated with OA (bone marrow lesions, osteophytes, minor cartilage defects and Hoffa-synovitis), quantified cartilage composition (T1ρ relaxation times) in the PFJ and perfusion within the patellar bone were examined using different MRI techniques. Associations were analyzed using regression analyses, adjusted for potential confounders. RESULTS Lateral patellar tilns Ltd.BACKGROUND Recent literature has reported intramuscular tendon (IT) disruption is associated with longer return to play (RTP) following acute hamstring injury. OBJECTIVES Investigate whether an increase in hamstring injury severity involving high-grade IT disruption and proximal injury location is associated with longer RTP times in elite Australian Rules Football (AFL) players. METHODS Hamstring injury records and RTP times from one professional AFL club were obtained over six seasons. MRI of injuries was retrospectively reviewed by a musculo-skeletal radiologist blinded to RTP information. A simplified four-grade classific

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