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https://www.selleckchem.com/products/MK-1775.html This study analysed the competition scheduling of future top 100 and 250 ranked tennis players from international tournament profiles at ages 13-18y. Retrospective tournament data were analysed for 165 future top 100 (T100) and top 250 (T250) males during their junior international tournament eligibility. Tournament/match volumes, days between tournaments and consecutive tournaments (0.05). Significant main effects were observed for age on tournament volume, with junior and professional volume increasing at age 15 and 17, respectively (p less then 0.05). Higher match volumes were observed for T100 players compared to T100-S players (p less then 0.05). Competition schedules intensify at age 15 compared with ages 13-14y through increased tournament and match volumes. Future T100 players' transition to professional tournaments earlier, alongside greater engagement in higher quality junior tournaments.In this special issue paper we reflect on the next generation of attachment research with a focus on disorganization, a central but still poorly understood topic in this area. We suggest that progress will be facilitated by a return to attachment theory's evolutionary roots, and to the emphasis on biological function that inspired Bowlby's original thinking. Increased interdisciplinary cross-fertilization and collaborations would enable novel and generative research on some of the long-standing questions surrounding attachment disorganization. Accordingly, we present an agenda for future research that encompasses contributions of modern ethology and neurobiology, novel hypotheses based on the concept of adaptive decanalization, connections with neurodevelopmental vulnerability and risk for mental disorders such as schizophrenia, and the possibility of sex differences in the behavioral manifestations of attachment disorganization. We believe that these avenues of theory and research offer exciting potential for innovative wo

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