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https://www.selleckchem.com/products/azd-9574.html Risk factors for severe SARS-CoV2 infection in pregnancy have not been extensively studied. This information can help guide the management of pregnant women with COVID-19. Examine risk factors for severe COVID-19 in pregnant women. We reviewed the records of all pregnant women with positive SARS-CoV2 tests (qRT-PCR) managed at a single tertiary private maternity in Sao Paulo, Brazil. We categorized women as having non-severe (mild or moderate) or severe (severe or critical) COVID-19. We conducted multivariable analyses to identify differences in sociodemographic and clinical characteristics of the two groups as risk factors for severe COVID-19. Between March 13 and June 7 2020, 114 women tested positive for SARS-CoV-2; 80.7% ( = 92) had non-severe disease (69 mild, 23 moderate), 15.7% ( = 18) had severe, and 3.5% ( = 4) had critical COVID-19. Women with severe/critical COVID-19 ( = 22) were significantly older (35.0 ± 5.9 × 31.8 ± 5.1 years, = 0.011), more likely to have at least one medicarisk factors for, while higher gestational age was protective against severe/critical COVID-19 in pregnant Brazilian women. The primary objective was to describe the incidence, symptoms, clinical signs, and time of onset of neonatal pneumothorax in Örebro County during 2011-2017. Secondary objectives were to describe risk factors, diagnostic procedures, treatments, and mortality and to compare preterm with term/post-term neonates. This retrospective population-based descriptive study included all neonates born in Örebro County during 2011-2017 and admitted to the neonatal intensive care unit at Örebro University Hospital at age <28 days with an x-ray verified diagnosis of "Pneumothorax originating in the perinatal period" in their medical record. Seventy-five neonates matched the inclusion criteria. The incidence of neonatal pneumothorax in Örebro County during the study period was 3.1 (95% CI 2.5-3.8) per 1000 live births. A
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