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https://www.selleckchem.com/products/Vorinostat-saha.html Multiple phantom stands were also 3D-printed using PLA for precise orientation of the phantom with respect to the direction of the static magnetic field. Acquisitions at different phantom angles, across multiple MRI systems, and with different pulse sequence parameters were evaluated. The variability between any two R2* measurements, taken in the same vial under these various acquisition conditions, on a 1.5 T MRI system, was less then 7% for each of the four vials. For 3 T MRI systems, variability was less than 14% in all cases. Variability was less then 6% for both 1.5 and 3 T acquisitions when unchanged pulse sequence parameters were used. The phantom can be used to mimic a range of clinically relevant levels of R2* relaxation rates, as measured using MRI. These measurements were found to be reproducible relative to the gold-standard method, liver biopsy, across several different image acquisition conditions. To investigate the feasibility and practicality of ultraviolet (UV) germicidal irradiation of the inner bore of a computed tomography (CT) gantry as a means of viral decontamination. A UV lamp (PADNUT 38W, 253nm UV-C light tube) and UV-C dosimeter (GENERAL UV-C Digital Light Meter No. UV512C) were used to measure irradiance throughout the inner bore of a CT scanner gantry. Irradiance (units μW/cm ) was related to the time required to achieve 6-log viral kill (10 survival fraction). A warm-up time of ~120s was required for the lamp to reach stable irradiance. Irradiance at the scan plane (z=0cm) of the CT scanner was 580.9μW/cm , reducing to ~350μW/cm at z=±20cm toward the front or back of the gantry. The angular distribution of irradiation was uniform within 10% coefficient of variation. A conservative estimate suggests at least 6-log kill (survival fraction≤10 ) of viral RNA within ±20cm of the scan plane with an irradiation time of 120s from cold start. More conservatively, running the lamp for 180s

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