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https://www.selleckchem.com/products/gsk3787.html Shear wave elastography (SWE) might allow non-invasive assessment of cardiac stiffness by relating shear wave propagation speed to material properties. However, after aortic valve closure, when natural shear waves occur in the septal wall, the stiffness of the muscle decreases significantly, and the effects of such temporal variation of medium properties on shear wave propagation have not been investigated yet. The goal of this work is to fundamentally investigate these effects. To this aim, qualitative results were first obtained experimentally using a mechanical setup, and were then combined with quantitative results from finite difference simulations. The results show that the amplitude and period of the waves increase during propagation, proportional to the relaxation of the medium, and that reflected waves can originate from the temporal stiffness variation. These general results, applied to literature data on cardiac stiffness throughout the heart cycle, predict as a major effect a period increase of 20% in waves propagating during a healthy diastolic phase, whereas only a 10% increase would result from the impaired relaxation of an infarcted heart. Therefore, cardiac relaxation can affect the propagation of waves used for SWE measurements and might even provide direct information on the correct relaxation of a heart.This work investigates anomalous transmission effects in periodic dissipative media, which is identified as an acoustic analogue of the Borrmann effect. For this, the scattering of acoustic waves on a set of equidistant resistive sheets is considered. It is shown both theoretically and experimentally that at the Bragg frequency of the system, the transmission coefficient is significantly higher than at other frequencies. The optimal conditions are identified one needs a large number of sheets, which induce a very narrow peak, and the resistive sheets must be very thin compared to the wavelength, wh

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