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https://www.selleckchem.com/products/danicopan.html 47 ± 174.39 N) (p ⟨ 0.001). A statistically significant difference was observed considering the failure mode (p = 0.036), with more favorable fractures detected with Group P. The tested novel endocrown system improved the biomechanical behavior of the tooth/ restoration complex in the restored endodontically treated maxillary first premolars. The tested novel endocrown system with a PEKK coping veneered with cemented IPS e.max CAD can be considered a promising option for restoration of severely-destructed endodontically treated premolar teeth. It can be considered as a conservative alternative option to the conventional treatment modalities. The tested novel endocrown system with a PEKK coping veneered with cemented IPS e.max CAD can be considered a promising option for restoration of severely-destructed endodontically treated premolar teeth. It can be considered as a conservative alternative option to the conventional treatment modalities. To describe prevalence of anterior tooth loss and its determinants among Chilean people aged over 15 years. Cross-sectional study, using the sampling frame of the Chilean National Health Survey 2016-2017 (n=5473 participants). Multivariate logistic regressions were performed to obtain the prevalence and odds ratio (OR) for anterior tooth loss using a complex sampling method. We described anterior tooth loss affecting each jaw according to sex, age, educational level, urban/rural residence and having health insurance. The odds of anterior tooth loss were 7.11 (95%CI 4.57 - 10.78) and 4.84 (95%CI 3.02 - 7.72) times higher for low-educated subjects compared to those with more educational, for the upper and lower jaw respectively. Also, the odds of anterior tooth loss for the upper jaw was 1.34 (CI 95% 1.07 - 1.66) times higher in women, whereas for the lower jaw, no significant differences by sex were found (p-value 0.14). Adults having only the National Health Fund B insurance (FO

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