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https://www.selleckchem.com/products/abt-199.html The phrase "I can't breathe" has become a national slogan in recent months for those who are protesting against racial discrimination across the world. For clinicians caring for neonates, this phrase should serve as a reminder about the stark disparities in health outcomes and health services for black infants and their families that have persisted for decades in spite of a voluminous amount of literature describing these disparities and the factors contributing to them. It should galvanize us into action within the neonatal intensive care unit and beyond to ensure equal treatment for all patients and their families, and to take measures to compensate for the disparities.To analyze the association of IL-1β with recurrence after the first epileptic seizure in ischemic stroke patients and evaluate its predictive value. 238 patients with the first epileptic seizure after ischemic stroke were included in this study. IL-1β expression levels were detected through quantitative Real-Time PCR. Kaplan-Meier method was used to perform univariate analysis with log-rank test. The variables with P  less then  0.1 were then included in multivariate analysis. Receiver operating characteristic (ROC) curve was used to evaluate the predictive value. Among all 238 patients, 107 patients (44.96%) had seizure recurrence and 131 patients (55.04%) had no recurrence. Kaplan-Meier analysis showed that high expression of IL-1β, low age ( less then  65 years), male, cortical involvement, large lesion size, late onset, severe neurological impairment and partial seizure type were associated with seizure recurrence. Multivariate analysis showed that IL-1β expression level (hazard ratio 2.057, 95% confidence interval 1.296-3.318) was independently associated with seizure recurrence. The area under ROC curve (AUC) was 0.803 (SE 0.030, 95% confidence interval 0.744-0.862) when IL-1β expression levels were applied in predicting seizure recurrence. IL-

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