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https://www.selleckchem.com/products/lee011.html Supportive treatment is necessary both before, during and after invasive causal treatment, it mainly involves the transfusion of leukocyte-depleted blood components, the use of anti-infectious prophylaxis or treatment of infections. In many cases AA, supportive therapy is the only therapeutic option, especially in elderly patients with comorbidities. In this paper we present current supportive treatment in this life-threatening disease. Quarantine is an effective measure to contain the spread of infectious disease, however, it can be a great challenge for patients undergoing maintenance hemodialysis (MHD). The purpose of this study was to evaluate the impact of hospital-based group medical quarantine (H-GMQ) on blood pressure (BP) in MHD patients, and the effect of age on change in BP. MHD patients in our dialysis center who were under H-GMQ due to exposure to coronavirus disease 2019 (COVID-19) were enrolled. Their demographic data, clinical characteristics, and laboratory data were collected from 3 months before H-GMQ to the end of H-GMQ. They were divided into two groups by median age (61 y). BP and related data before and during H-GMQ between groups were analyzed. The association between age and change in BP was estimated using multivariable linear regression analysis. One hundred and thirty MHD patients were enrolled. The pre-dialysis systolic BP (SBP) and heart rate (HR) during H-GMQ were significantly higher than before, the serum sodium decreased significantly at the end of H-GMQ. After adjusting for covariates by multivariable regression, age had a negative correlation with BP elevation (R2 =0.218, P=0.246). Subgroup analysis showed that both pre-dialysis SBP and diastolic BP (DBP) increased significantly during H-GMQ in patients less than 61 years old, instead, neither SBP nor DBP changed in the elderly. H-GMQ increased the pre-dialysis BP in MHD patients, especially in younger patients. More attention shoul

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