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https://www.selleckchem.com/products/epacadostat-incb024360.html Therefore, body thickness should be considered under the AEC system for introducing EI as the dose optimization tool in digital chest radiography.Scientific names are not part of everyday language in any modern country, and their input as strings in a query system can be easily associated with typographical errors. While globally unique identifiers univocally address a taxon name, they can hardly be used for querying a database manually. Thus, matching algorithms are often used to overcome misspelled names in query systems in several data repositories worldwide. In order to improve users' experience in the use of FlorItaly, the Portal to the Flora of Italy, a near match algorithm to resolve misspelled scientific names has been integrated in the query systems. In addition, a novel tool in FlorItaly, capable of rapidly aligning any list of names to the nomenclatural backbone provided by the national checklists, has been developed. This manuscript aims at describing the potential of these new tools.Breast cancer (BC) is the most common cancer diagnosed in women worldwide. Approximately 70% of BC patients have the luminal subtype, which expresses hormone receptors (HR+). Adjuvant endocrine treatments are the standard of care for HR+/HER2- BC patients. Over time, approximately 30% of those patients develop endocrine resistance and metastatic disease. Cyclin-dependent kinase inhibitors (CDKi), in combination with an aromatase inhibitor or fulvestrant, have demonstrated superior efficacies in increasing progression-free survival, with a safe toxicity profile, in HR+/HER2- metastatic BC patients. CDKi blocks kinases 4/6, preventing G1/S cell cycle transition. However, not all of the patients respond to CDKi, and those who do respond ultimately develop resistance to the combined therapy. Studies in tumour tissues and cell lines have tried to elucidate the mechanisms that underlie this progression, but there are

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