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https://www.selleckchem.com/products/AZD0530.html Oral bacterial lysates (OBLs) can reduce the frequency and severity of recurrent respiratory tract infections in children from viral and bacterial origins. OBL-induced early innate immune reaction was already shown, but the specific features of different OBLs have never been studied and compared. A study was conducted to assess in vitro the protective effects on rhinovirus- (RV-) infected human bronchial epithelial cells (BECs) of two slightly different OBLs OM-85 and Pulmonarom. Furthermore, since immune cells represent the key arm for antiviral defence, the capacity of these OBLs to induce selected cytokine production in mouse bone marrow-derived DCs (BMDCs) was also evaluated. Although different OBLs may share some mechanisms to protect host cells from virus infection, some product-specific antimicrobial activities were observed on RV-infected human BECs and mouse BMDCs. These results are consistent with a product-specific response possibly triggered by different pathogen-associated molecular patterns (PAMPs) contained in OBLs.Home gardens are recognised in the literature for their contribution to food security, yet the process by which agrobiodiversity and household characteristics mediate this relationship is less well understood. This paper contributes to fill this research gap by drawing on a multi-site case study in the Yucatán region in Mexico. By applying regression analysis, the significance of the association between home garden diversity and food security is confirmed. Plant diversity is found to have a positive association with food consumption scores and the frequency of vegetable intakes. The number of animals used for food purposes is also found to have positive and significant associations with food consumption scores and frequency of meat intakes. However, the dimension and the significance of these positive associations were found to vary among communities and quantiles of the distribution of food
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