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https://www.selleckchem.com/products/nibr-ltsi.html Conclusion CMRI is able to detect even small, clinically asymptomatic cardiac metastases in young patients affected by osteosarcoma. © 2020 The Authors. Published by Elsevier Inc. on behalf of University of Washington.Objective The purpose of this meta-analysis was to determine whether platelet-rich plasma (PRP) was better than hyaluronic acid (HA) for the treatment of knee osteoarthritis (OA) in overweight or obese patients. Design Two reviewers independently used the keywords combined with free words to search English-based electronic databases according to Cochrane Collaboration guidelines, such as PubMed, Embase, ScienceDirect, and Cochrane library. The pooled data were analyzed using RevMan 5.3. Results Ten randomized controlled trials (RCTs) with 1096 patients were included. During the first two months of follow-up, there was no significant difference between the two groups. At the 3rd, 6th, and 12th months of follow-up, the pooled analysis showed that PRP was better than HA for the treatment of knee OA in overweight or obese patients. There were significant differences between the two groups at Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score (3 months MD = -1.35, [95% CI -2.19 to -0.50], P=0.002, I 2 = 0%; 6 months MD = -7.62, [95% CI -13.51 to -1.72], P=0.01, I 2 = 88%; 12 months MD = -12.11, [95% CI -20.21 to -4.01], P=0.003, I 2 = 94%). Conclusions For overweight or obese patients with knee OA, intra-articular injection of PRP in a short time was not necessarily superior to HA, but long-term use was better than HA in pain and functional relief. Copyright © 2020 Pan Luo et al.Catastrophic thinking is related to pain intensity and the degree of disability and influences pain care significantly. However, only few studies have investigated the impact of catastrophic thinking on chronic pain (CP) in the community-dwelling elderly population. This study aimed to evaluate the c

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