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https://www.selleckchem.com/products/agk2.html The magnitude, timing, and etiology of morbidity associated with tropical cyclones remains incompletely quantified. We examined the relative change in cause-specific emergency department (ED) visits among residents of New York City during and after Hurricane Sandy, a tropical cyclone that affected the northeastern United States in October 2012. We used quasi-Poisson constrained distributed lag models to compare the number of ED visits on and after Hurricane Sandy to all other days, 2005-2014, adjusting for temporal trends. Among residents aged ≥ 65 years, Hurricane Sandy was associated with a higher rate of ED visits due to injuries and poisoning (RR 1.19, [95% CI 1.10, 1.28]), respiratory disease (1.35, [1.21, 1.49]), cardiovascular disease (1.10, [1.02, 1.19]), renal disease (1.44, [1.22, 1.72]), and skin and soft tissue infections (1.20, [1.03, 1.39]) in the first week following the storm. Among adults aged 18-64 years, Hurricane Sandy was associated with a higher rate of ED visits for renal disease (2.15, [1.79, 2.59]). Among those aged 0-17, the storm was associated with lower rates of ED visits for up to three weeks. These results suggest that tropical cyclones may result in increased healthcare utilization due to a wide range of causes, particularly among older adults.Less-intensive induction therapies are increasingly used in older patients with acute myeloid leukemia, assuming they are better than intensive induction. Using an AML-composite model (AML-CM) that assigns higher scores to older age, increased comorbidity-burdens and adverse cytogenetic-risks, we defined three distinct prognostic groups, and within each, compared outcomes after less-intensive versus intensive induction therapies in a multicenter retrospective cohort (n=1292) treated at six institutions from 2008-2012 and a prospective cohort (n=695) treated at thirteen institutions from 2013-2017. Prospective study included impacts of Karnofsky perf

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