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https://www.selleckchem.com/products/Temsirolimus.html BACKGROUND The term "community health worker" (CHW) can apply to a wide range of individuals providing health services and support for diverse populations. Very little is known about the role of CHWs in Europe working in nonclinical settings who promote sexual health and prevent HIV and other sexually transmitted infections (STIs) among gay, bisexual, and other men who have sex with men (MSM). OBJECTIVE This paper describes the development and piloting of the first European Community Health Worker Online Survey (ECHOES) as part of the broader European Union-funded ESTICOM (European Surveys and Trainings to Improve MSM Community Health) project. The questionnaire aimed to assess the knowledge, attitudes, and practices of CHWs providing sexual health services to gay, bisexual, and other MSM in European settings. METHODS ECHOES comprises three superordinate domains divided into 10 subsections with 175 items (routed) based on a scoping exercise and literature review, online prepiloting, and Europe-wide consultatict and provide recommendations for MSM-specific strategies to improve sexual health in general and to reduce the incidence and prevalence of HIV, viral hepatitis, and other STIs in particular. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) RR1-10.2196/15012. ©Nigel Sherriff, Jorg Huber, Nick McGlynn, Carrie Llewellyn, Alex Pollard, Nicolas Lorente, Cinta Folch, Caoimhe Cawley, Oksana Panochenko, Michael Krone, Maria Dutarte, Jordi Casabona. Originally published in JMIR Research Protocols (http//www.researchprotocols.org), 18.02.2020.BACKGROUND Early detection or notification of adverse event (AE) occurrences during clinical trials is essential to ensure patient safety. Clinical trials take advantage of innovative strategies, clinical designs, and state-of-the-art technologies to evaluate efficacy and safety, however, early awareness of AE occurrences by investigators still needs to be systematically impr

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