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https://www.selleckchem.com/products/fin56.html Collectively, our study demonstrated that low dose of NaAsO2 exacerbated DON-induced intestinal barrier impairment in vivo and in vitro. The present study also demonstrated that activation of AhR-mediated autophagy might be a self-protection mechanism. Hence, AhR and autophagy might be novel therapeutic targets to prevent or alleviate NaAsO2 combined with DON-induced intestinal barrier impairment.This study aims to identify methane (CH4) emission flows along global supply chains from both production- and consumption-based perspectives and their temporal changes from 2000 to 2014. We employed the structural path analysis (SPA) method to examine the embodied CH4 emission trade through inter-sectoral and inter-regional supply chains. Production activities in the sector of Agriculture (such as crop and animal production) and consumption activities in Construction (such as infrastructure) were the most significant contributors to global CH4 emission increases during 2000-2014. Agriculture and Mining (such as coal mining) accounted for large shares of global embodied CH4 trade at the final consumption tier (i.e., the trade of final goods or services), while Food (such as beverages and tobacco) and Heavy manufacturing (such as steel or automobile manufacturing) were significant contributors to embodied CH4 emissions in the trade of intermediate goods or services directly used to produce final goods or services. This finding highlights the different potential of the sectors for CH4 abatement along global supply chains. The United States imported the most embodied CH4 emissions from foreign areas in 2000 in contrast to China, which dominated imports in 2014. Over 80% of China's embodied CH4 emissions in 2014 were related to intermediate production along global supply chains due to industrial upgrading. India surpassed China as the largest direct emitter for producing final goods or services. Given the critical role of non-CO2 g

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