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https://www.selleckchem.com/products/relacorilant.html 7 (95% CI -6.90 to -2.50) and effect size was 1.04 in favor to PFMT. Manometry also presented improvement after treatment for both groups with mean difference between them of 11 (95% CI 6.33-15.67) and effect size was 1.15 also in favor to PFMT. Regarding to SUI symptoms, quality of life impact and PFM function both groups presented improvement, however, PFMT was superior to AHT among all of them. Regarding to SUI symptoms, quality of life impact and PFM function both groups presented improvement, however, PFMT was superior to AHT among all of them. The effectiveness and safety of mouthguards are affected by their thickness. The aim of this study was to investigate the effect of an acute angle model on the mouthguard thickness with the thermoforming method in which the model position was moved just before fabrication. Mouthguards were thermoformed using 4.0mm thick ethylene vinyl acetate sheets and a vacuum forming machine. Three hard plaster models were prepared 1) the angle of the labial surface to the model base was 90°, and the anterior height was 25mm (model A); 2) the angle was 90°, and the anterior height was 30mm (model B); and 3) the angle was 80°, and the anterior height was 30mm (model C). The sheet was softened until it sagged 15mm, after which the sheet frame was lowered to cover the model. The model was then pushed from behind to move it forward, and the vacuum was switched on (MP). The model was moved 20mm whereas a control model was not moved. Mouthguard thickness was measured using a specialized caliper. The differences in mouthguard thicknesses due to model forms and forming conditions were analyzed by two-way ANOVA and Bonferroni's multiple comparison tests. The MP tended to be thicker than the control in all models. In the controls, model C was significantly thicker than models A and B at the labial and buccal surfaces. In MP, model A was significantly thicker than models B and C on the labia

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