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Bone marrow mesenchymal stem cells (BMSCs), as seed cells, have played an important role in bone defect repair. However, efficiently amplifying and inducing BMSCs in vitro or vivo remains an urgent problem to be solved. Electrical stimulation has been beneficial to the proliferation and differentiation of BMSCs, but current electrical stimulation methods have a critical disadvantage in that they usually burn the skin. g-C3N4/rGO, a new photosensitive material, can produce photocurrent under natural light irradiation, thus reducing energy consumption. Our purpose was to explore whether this photocurrent can promote the proliferation and differentiation of BMSCs. g-C3N4/rGO synthesised under high temperature and pressure had negligible cytotoxicity as confirmed by methyl thiazolyl tetrazolium to BMSCs. Better osteogenesis was found in the blue light material group than in the light-shielding material group, exhibited by alizarin red staining, alkaline phosphatase activity, Western-Blot, and RT-qPCR. Animal experiments showed that the bone repair potential of the material group was significantly higher than that of the non-material group. Overall, we conclude that g-C3N4/rGO is a new non-toxic photosensitive material which can rapidly induce BMSCs into osteoblasts, accelerating bone regeneration and providing us with a feasible method of rapid bone repair.Marine macroalgae are cultivated for diverse applications, from biofuel and biogas to biofiltering, from food to cosmetics or pharmaceuticals. Since macroalgae cultivation does not compete with land-based food crops for the necessary arable land or fresh water, it can increase the possibilities of sustainably harvested biomass. New technologies permit even land-based growing of marine macroalgae, besides the more common coastal or offshore cultivation. All these technologies, however, raise the question of how to provide ideal cultivation conditions, especially for adherent macroalgae, and of how to harvest them economically and sustainably. While some reports about growing marine macroalgae on diverse textile materials, such as polyester ropes or polypropylene nets, can be found in the literature, we report here for the first time on the growth of a marine macroalga on knitted fabrics. In our study, Ectocarpus sp. was cultivated in shallow rectangular cultivation vessels on knitted fabrics of various materials and structures revealing a significant influence of both parameters. Undesired changes of the pH value in the cultivation system as well as foam generation were attributed to textile auxiliaries. Considering all these influences, the best-suited knitted fabrics were identified as open-pore structures from hairy yarns made partly or completely from natural fibres.Objective To examine the allocation of daily activities over a 24-hour period in caregivers (CGs) with and without a probable affective disorder. Methods Participants were 192 older dementia CGs (mean age = 72.9 years, 70% female) who participated in the National Study of Caregiving. Time diary data were used to measure the duration and timing that caregivers were doing hygienic self-care, eating/drinking, household care, physical caregiving, medical caregiving, socializing, and television viewing. Affective status was assessed using the two-item Patient Health Questionnaire and the Generalized Anxiety Disorder screeners. Results CGs were more likely to screen positive for depression/anxiety symptoms if they started hygienic self-care later (OR = 1.76, 95% CI = 1.10-2.83) and started medical caregiving later (OR = 2.34, 95% CI = 1.24-4.41). Hygienic self-care start times attenuated the effects of medical caregiving on the affective status. Discussion Later timing of hygienic self-care may be an important behavioral response that contributes to affective disorder risk in dementia CGs.Intimate partner violence (IPV) is a pervasive social challenge with severe health and demographic consequences. Global statistics indicate that more than a third of women have experienced IPV at some point in their lives. https://www.selleckchem.com/products/dmog.html In South Africa, IPV is considered a significant contributor to the country's broader problem with violence and a leading cause of femicide. Consequently, IPV has been the major focus of legislation and research across different disciplines. The present article aims to contribute to the growing scholarly literature by predicting factors that are associated with the risk of experiencing IPV. We used the 2016 South African Demographic and Health Survey dataset and restricted our analysis to 1,816 ever-married women who had complete information on the variables that were used to generate IPV. Prior research has mainly used regression analysis to identify correlates of IPV; however, while regression analysis can test a priori specified effects, it cannot capture unspecified inter-relationship across factors. To address this limitation, we opted for machine learning methods, which identify hidden and complex patterns and relationships in the data. Our results indicate that the fear of the husband is the most critical factor in determining the experience of IPV. In other words, the risk of IPV in South Africa is associated more with the husband or partner's characteristics than the woman's. The models developed in this study can be used to develop interventions by different stakeholders such as social workers, policymakers, and or other interested partners.Interactions with staff are important aspects in patients' experiences of psychiatric inpatient care (PIC). This study aimed to evaluate patients' satisfaction with their interactions with PIC staff and whether sociodemographic factors, depression and anxiety symptoms were associated with their perceptions of these interactions. In this cross-sectional study, we collected data from 84 patients receiving inpatient care in three psychiatric settings in Sweden. The patients' perceptions of interactions with staff and self-reported degrees of depression and anxiety were evaluated through questionnaires. Overall, patients were satisfied with the patient-staff interaction. However, significantly higher scores were related to staffs' practical competence than to their compassion. Older patients reported significantly more satisfaction than younger patients with their most recent meeting with staff. Tailored nursing interventions may improve staff's compassionate capacity. Further research in larger samples is needed to improve our understanding of the factors associated with how patients perceive their interactions with staff.
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