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https://www.selleckchem.com/ https://www.selleckchem.com/ Function regarding Hypoxia from the Power over the Mobile or portable Routine. Compared to conventional full sternotomy (FS) approaches, minimally invasive mitral valve surgery (MIMVS) offers improved cosmesis, decreased pain and bleeding, and faster recovery, without compromising repair or survival rates. However, little is known about outcomes in patients with pulmonary hypertension (PH), an independent risk factor for morbidity and mortality. Retrospective review was performed between 2002 and 2019 for all adult patients undergoing isolated mitral valve (MV) surgery. Patients with PH (mean pulmonary artery pressure ≥ 25 mmHg) were stratified by FS or MIMVS and nearest-neighbor propensity score matching was performed to adjust for differences in baseline characteristics. Overall, 591 surgeries (317 MIMVS, 274 FS) met inclusion criteria during the study period. Nearest neighbor propensity matching generated 112 well-matched pairs. Cardiopulmonary bypass (137 vs 89.5 min, P < 0.001), cross clamp (102 vs 63 min, P < 0.001), and total operative times (241 vs. 178.5 min, p < 0.001) were longer for the MIMVS group. Postoperatively, MIMVS was associated with shorter initial ventilator times (6 vs 9.6 hrs, P < 0.001) and hospital lengths of stay (7 vs. 8 days, p = 0.049), as well as blood product utilization rates (26.8% vs. 41.1%, p = 0.03). Thirty-day (0.0% vs 2.7%, P = 0.12) and 10-year survival (Log-rank, P = 0.661) were similar between groups. MIMVS is safe in patients with PH and provides traditional benefits of minimally invasive surgery including shorter initial ventilator times and hospital LOS, without compromising on long-term survival. MIMVS is safe in patients with PH and provides traditional benefits of minimally invasive surgery including shorter initial ventilator times and hospital LOS, without compromising on long-term survival. Bronchoscopic valve placement constitutes an effective endoscopic lun
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