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https://www.selleckchem.com/products/sulbactam-pivoxil.html 25 publications focused on a specific subtype of rosacea, mainly papulopustular and ocular rosacea. The 100 articles were published in 32 journals. 79 different first corresponding authors were from 20 different countries, mostly in North America and Europe. Steinhoff. M from University of California published the most articles as the corresponding author. CONCLUSIONS This study identified the top 100 most cited articles in rosacea and analyzed their bibliometric characteristics, which may pave the way for further research. This article is protected by copyright. All rights reserved.BACKGROUND Few large studies have assessed spironolactone treatment of adult female acne. OBJECTIVES To explore the role of spironolactone in the treatment of adult female acne. METHODS We performed a retrospective case series assessing the efficacy of spironolactone treatment of a cohort of women evaluated at Mayo Clinic in Rochester, Minnesota, from 2007 through 2017. RESULTS In total, 395 patients (median age, 32 years) received a median spironolactone dose of 100 mg daily. Approximately two-thirds of patients (66.1%) had a complete response; 85.1% had a complete response or a partial response greater than 50%. Median times to initial response and maximum response were 3 and 5 months. Efficacy was observed across all severity subtypes of acne, including those with papulopustular and nodulocystic acne. Patients received long-term treatment with spironolactone (median duration, 13 months) and had few adverse effects. CONCLUSIONS Spironolactone is a safe and effective treatment of acne for women. © 2020 European Academy of Dermatology and Venereology.BACKGROUND Mutations in the γ-secretase enzyme subunits have been described in multiple kindreds with familial hidradenitis suppurativa (HS). OBJECTIVE In this study, we report a novel nicastrin (NCSTN) mutation causing HS in a Dutch family. We sought to explore the immunobiological

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