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https://www.selleckchem.com/mTOR.html 6% in 2013 to 21.1% in 2019. DDD-based usage of the CredibleMeds drugs already listed in 2013 was similar in 2019. Among the drugs with known QT risk according to CredibleMeds , 7.5% (95% CI 2.6-19.9%) of German SmPCs and 21.1% (95% CI 11.1-36.3%) of US PI had no mention of QT issues whatsoever. A significant proportion of all drugs prescribed in the outpatient sector is associated with QT risks according to CredibleMeds . SmPCs and PI should systematically be evaluated for concordance with the widely used CredibleMeds database to increase medication safety. A significant proportion of all drugs prescribed in the outpatient sector is associated with QT risks according to CredibleMeds® . SmPCs and PI should systematically be evaluated for concordance with the widely used CredibleMeds® database to increase medication safety. To present the technical details of the runner-up model in the open knowledge-based planning (OpenKBP) challenge for the dose-volume histogram (DVH) stream. The model was designed to ensure simple and reproducible training, without the necessity of costly advanced generative adversarial network (GAN) techniques. The model was developed based on the OpenKBP challenge dataset, consisting of 200 and 40 head-and-neck patients for training and validation, respectively. The final model is a U-Net with additional ResNet blocks between up- and down convolutions. The results were obtained by training the model with AdamW with the One Cycle scheduler. The loss function is a combination of the L1 loss with a feature loss, which uses a pretrained video classifier as a feature extractor. The performance was evaluated on another 100 patients in the OpenKBP test dataset. The DVH metrics of the test data were evaluated, where D 0.1 c c , andmputer vision techniques. Immune checkpoint inhibitors (ICIs) are an important treatment for metastatic renal cell carcinoma (mRCC). These agents may cause immune-related adverse events (i

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