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https://www.selleckchem.com/products/d609.html Darlington described Tiferonia based on T. parva from New Guinea. In this review, Tiferonia leytensis sp. nov. is described from Leyte Island, Philippines, Tiferonia schoutedeni (Straneo, 1943) comb. nov. is transferred from Melanchrous Andrewes, and inclusion of Tiferonia brunnea (Jedlička, 1935) in the genus is confirmed. Characteristics of Tiferonia and genera that have been proposed as closely related to Tiferonia are discussed and a unique character, the post-ocular sulcus, shared among species of Tiferonia and Holconotus is proposed as a synapomorphy for these two genera. A key to identify adults of the four species of Tiferonia is provided. Kipling W. Will.Beta-lactam allergy is commonly diagnosed in paediatric patients, but over 90% of individuals reporting this allergy are able to tolerate the medications prescribed after evaluation by an allergist. Beta-lactam allergy labels are associated with negative clinical and administrative outcomes, including use of less desirable alternative antibiotics, longer hospitalizations, increasing antibiotic-resistant infections, and greater medical costs. Also, children with true IgE-mediated allergy to penicillin medications are often advised to avoid all beta-lactam antibiotics, including cephalosporins, which is likely unnecessary in greater than 97% of those reporting penicillin allergies. Most patients can be safely treated with penicillin or amoxicillin if they do not have a history compatible with IgE-mediated or systemic, delayed reactions such as Stevens-Johnson syndrome (SJS), serum sickness-like reactions, drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, or acute generalized exanthematous pustulosis (AGEP). Guidance is provided on how to stratify risk of beta-lactam allergy, and on test dosing and monitoring in the outpatient setting for patients deemed low risk. Guidance for patients at higher risk of beta-lactam allergy includes criteria f
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