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Elite athletes face extreme challenges to perform at peak levels. Acute and chronic musculoskeletal injuries are an occupational hazard while pressures to return to play post-injury are commonplace. Therapeutic options available to elite athletes range from novel 'cutting edge' biomedical therapies, established biomedical and surgical techniques, and physiotherapy, to a variety of non-orthodox therapies. Little is known about how different treatment options are selected, evaluated, nor how their uses are negotiated in practice. We draw on data from interviews with 27 leading sports medicine physicians working in professional football and cycling in the UK, collected 2014-16. Using idea of the 'therapeutic landscape' as a conceptual frame, we discuss how non-orthodox tools, technologies and/or techniques enter the therapeutic landscape of elite sports medicine, and how the boundaries between orthodox and non-orthodox therapy are conceptualised and navigated by sports medicine practitioners. The data provide a detailed and nuanced examination of heterogenous therapeutic decision -making, reasoning and practice. Our data show that although the biomedical paradigm remains dominant, a wide range of non-orthodox therapies are frequently used, or authorised for use, by sports medicine practitioners, and this is achieved in complex and contested ways. Moreover, we situate debates around nonorthodox medicine practices in elite sports in ways that critically inform current theories on Complementary and Alternative Medicine (CAM)/biomedicine. We argue that existing theoretical concepts of medical pluralism, integration, diversity and hybridisation, which are used to explain CAMs through their relationships with biomedicine, do not adequately account for the multiplicity, complexity and contestation that characterise contemporary forms of CAM use in elite sport. BACKGROUND AND PURPOSE Our study aimed to compare the oncologic outcomes and toxicities between passive scattering (PS) proton beam therapy (PBT) and pencil-beam scanning (PBS) PBT for primary hepatocellular carcinoma (HCC). MATERIALS AND METHODS The multidisciplinary team for liver cancer identified the PBT candidates who were ineligible for resection or radiofrequency ablation. We retrospectively analyzed 172 patients who received PBT for primary HCC from January 2016 to December 2017. The PS with wobbling method was applied with both breath-hold and regular breathing techniques, while the PBS method was utilized only for regular breathing techniques covering the full amplitude of respiration. To maintain the balance of the variables between the PS and PBS groups, we performed propensity score matching. RESULTS The median follow-up duration for the total cohort was 14 months (range, 1-31 months). After propensity score matching, a total of 103 patients (70 in the PS group and 33 in the PBS group) were included in analysis. There were no significant differences in the rates of overall survival (OS), in-field local control (IFLC), out-field intrahepatic control (OFIHC), extrahepatic progression-free survival (EHPFS), and complete response (CR) between the matched groups. In the subgroup analyses, no subgroup showed a significant difference in IFLC between the PS and PBS groups. There was also no significant difference in the toxicity profiles between the groups. CONCLUSION There are no differences in oncologic outcomes, including OS, IFLC, OFIHC, EHPFS, and CR rates, or in the toxicity profiles between PS and PBS PBT for primary HCC. Soil erosion of sloped farmland in the Three Gorges Reservoir area (TGRA) has led to the serious loss of nutrients, soil quality degradation and the downstream water quality being threatened. Thus, a series of ecological agricultural engineering measures was established in 2011, as a field experiment using citrus (navel orange) plants to reduce soil erosion, which was monitored from 2011 to 2018. These ecological agricultural engineering measures included three treatments 1) citrus intercropped with white clover (WC), 2) citrus orchard land mulched with straw (SM) and 3) citrus intercropped with hemerocallis (Hemerocallis flava) contour hedgerows (CH). The conventional citrus orchard management was regarded as control (CK). The results show, that compared with CK, nutrient loss from the experiments were reduced by the following amounts for nitrogen - WC (35.5%), SM (44.0%) and CH (52.0%); for phosphorus - WC (40.0%), SM (51.7%) and CH (58.3%). Therefore, the ecological agricultural engineering measures effectively mitigate the nutrient loss loads of the navel orange citrus gardens. The citrus intercropped with the hemerocallis hedgerows is the most effective measure for the control of nutrient loss. After 8 years of experiment, the soil quality represented by average soil quality index (SQI) in these three treatments, are significantly higher than that of the CK (and the beginning of the experiment). This is because the application of these measures prevented the loss of soil organic matter, bulk density and total phosphorus. It is predicted that the soil qualities of these three treatments will remain in the range of soil grade II and I for the next 5 years but the soil quality of CK will decrease to soil quality grade II and III. These results show that ecological agricultural engineering measures are a long-term promising and feasible method to reduce soil erosion and enhance soil quality. The adsorption of phosphate on hydrated ferric oxide (HFO) was studied in solutions containing major seawater ions (Na+, Mg2+, Cl-, SO42-, Ca2+, K+) at pHs 6.5, 7.5 and 8.5. The presence of these ions promotes phosphate adsorption and the process is electrostatic in nature. Despite this electrostatic force, the precipitation of hydroxyapatite in the presence of Ca2+ at pH 8.5 also plays an important role in the removal of phosphates from the dissolved phase. Energy dispersive X-ray spectroscopy (EDS) and Fourier transform infrared (FTIR) spectra support that phosphate adsorption on HFO surface can be attributed to inner sphere complexes with the formation of bidentate complexes (FeO)2PO2 in the presence of main seawater ions at pH = 8.5. https://www.selleckchem.com/products/epz-5676.html The results of EDS clearly indicated that Fe-P-Ca complexes, Fe-P-Mg, or other phosphate-bridged ternary complexes were not formed during adsorption in the presence of NaCl, KCl, CaCl2, Na2SO4 and MgCl2. This observation differs somewhat from that the typical explanation used to describe the phosphate adsorption mechanism on HFO.
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