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https://www.selleckchem.com/products/miransertib.html Numerous missions planned for the next decade are likely to target a handful of small sites of interest on the Moon's surface, creating risks of crowding and interference at these locations. The Moon presents finite and scarce areas with rare topography or concentrations of resources of special value. Locations of interest to science, notably for astronomy, include the Peaks of Eternal Light, the coldest of the cold traps and smooth areas on the far side. Regions richest in physical resources could also be uniquely suited to settlement and commerce. Such sites of interest are both few and small. Typically, there are fewer than ten key sites of each type, each site spanning a few kilometres across. We survey the implications for different kinds of mission and find that the diverse actors pursuing incompatible ends at these sites could soon crowd and interfere with each other, leaving almost all actors worse off. Without proactive measures to prevent these outcomes, lunar actors are likely to experience significant losses of opportunity. We highlight the legal, policy and ethical ramifications. Insights from research on comparable sites on Earth present a path toward managing lunar crowding and interference grounded in ethical and practical near-term considerations. This article is part of a discussion meeting issue 'Astronomy from the Moon the next decades'.The Earth's moon is currently an object of interest of many space agencies for unmanned robotic missions within this decade. Besides future prospects for building lunar gateways as support to human space flight, the Moon is an attractive location for scientific purposes. Not only will its study give insight on the foundations of the Solar System but also its location, uncontaminated by the Earth's ionosphere, represents a vantage point for the observation of the Sun and planetary bodies outside the Solar System. Lunar exploration has been traditionally conducte

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