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https://www.selleckchem.com/products/danicopan.html CONCLUSION We present the first published case of intravenous poppers abuse. Our patient suffered from methaemoglobinaemia and was rapidly discharged after treatment with toluidine blue. No specific treatment regarding the contents of the poppers bottle, apart from isopropyl nitrite, was necessary. © Royal College of Physicians 2020. All rights reserved.Thrombolytic treatment with tissue plasminogen activator is an established therapy for selected patients with ischaemic stroke within a narrow time window of 3 hours from the onset of symptoms. However, severe complications and poor outcomes are likely to ensue if a patient with acute aortic dissection is inadvertently treated with thrombolytic agents.We describe a patient presenting as facial droop, arm weakness, speech disturbance and time to call emergency services (FAST) positive (clinical picture of ischaemic stroke) who received thrombolysis and in whom the underlying diagnosis of acute thoracic aortic dissection was made by a combination of chance and a high clinical suspicion. © Royal College of Physicians 2020. All rights reserved.A 31-year-old man presented with central chest heaviness. He was a smoker of 15 pack-years, but otherwise had no other comorbidities. He was also a professional footballer. There was no family history of sudden cardiac deaths of note. In view of a low to intermediate pre-test probability for coronary artery disease (CAD), computed tomography coronary angiography (CTCA) was performed, revealing an anomalous, malignant right coronary artery (RCA), originating from the left main coronary stem. Malignant RCAs are rare, and the majority of patients remain asymptomatic. However, malignant RCAs have been associated with both myocardial infarctions and sudden cardiac deaths, which has led to difficulty in deciding on whether a 'watchful waiting' approach or more proactive approach should be adopted. Unfortunately, there remains a lack of

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