Yam Code

New Paste Browse

https://www.selleckchem.com/products/CHR-2797(Tosedostat).html Many types of long-acting injectables, including in situ forming implants, preformed implants, and polymeric microparticles, have been developed and ultimately benefited numerous patients. The advantages of using long-acting injectables include greater patient compliance and more steady state drug plasma levels for weeks and months. However, the development of long-acting polymeric microparticles has been hampered by the lack of understanding of the microparticle formation process, and thus, control of the process. Of the many parameters critical to the reproducible preparation of microparticles, the interfacial tension (IFT) effect is an important factor throughout the process. It may influence the droplet formation, solvent extraction, and drug distribution in the polymer matrix, and ultimately drug release kinetics from the microparticles. This mini-review is focused on the IFT effects on drug-loaded poly(lactic-co-glycolic acid) (PLGA) microparticles.The use of natural biocompatible drugs is highly desirable in wound dressing compared to synthetic chemicals. Oregano essential oil (OEO) is a promising natural compound with marked antibacterial, antioxidant and anti-inflammatory activities. The topical delivery of OEO may result in lower therapeutic efficacy and irritation to the skin. Moreover, OEO is a volatile compound results in instability as well. To overcome these drawbacks, we successfully encapsulated OEO in Poly (L-lactide-co-caprolactone) (PLCL)/ Silk fibroin (SF) nanofibers membrane (NF) and achieved the encapsulation efficiency (%) up to 59.14 ± 0.58. The fabricated membranes were undergone through physicochemical as well as biological evaluation. SEM characterization revealed that OEO could be successfully encapsulated maintaining a smooth profile of nanofibers. The biocompatibility of the NF membrane was confirmed by cytotoxicity assay. Antibacterial results indicated that OEO containing

Paste Settings

Paste Title : [Optional]

Paste Folder : [Optional]

Syntax Highlighting : [Optional]

Paste Expiration : [Optional]

Paste Status : [Optional]

Password : [Optional]

Description: [Optional]

Tags: [Optional]

Encrypt Paste (?)

You are currently not logged in, this means you can not edit or delete anything you paste. Sign Up or Login

Paste Settings

Site Languages