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https://www.selleckchem.com/products/sodium-acrylate.html Additionally, the level of TET is upregulated. Consistent with the upregulation of αKG production and TET, we observed a genome-wide increase in 5-hydroxymethylcytosine (5hmC), which is an intermediate in DNA demethylation. Moreover, the DNA methylation level of ES-cell super-enhancers of pluripotency-related genes is significantly decreased, leading to the upregulation of associated genes. Finally, the transduction of TET and the administration of cell-permeable αKG to somatic cells synergistically enhance cell reprogramming by Yamanaka factors. These results suggest the possibility that the activation of AKT during somatic cell reprogramming promotes epigenetic reprogramming through the hyperactivation of TET at the transcriptional and catalytic levels. These results suggest the possibility that the activation of AKT during somatic cell reprogramming promotes epigenetic reprogramming through the hyperactivation of TET at the transcriptional and catalytic levels. Carbon dots (C-dots) are photoluminescent nanoparticles with less than 10nm in size. Today, many studies are performed to exploit the photoluminescence (PL) property of carbon dots, and our focus in this study is to estimate the dipole moment of carbon dots. For reaching our aims, C-dots were synthesized and dissolved in the different solvents. Carbon dots with intense photoluminescence properties have been synthesized by a one-step hydrothermal method from a carbon bio-source. In this research, we report on the effect of aprotic solvents on absorption and fluorescence spectra and dipole moments of C-dots dispersed in a range of many aprotic solvents with various polarity and dielectric constant at room temperature. The change in the value of dipole moment was estimated by using the Stokes shifts. The difference between the dipole moment of the excited state and the ground state was shown using an extended form of Lippert equations by Kawski and co-

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