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https://www.selleckchem.com/products/LY315920(Varespladib).html The International Brain Laboratory (IBL) is a collaboration of ∼20 laboratories dedicated to developing a standardized mouse decision-making behavior, coordinating measurements of neural activity across the mouse brain, and utilizing theoretical approaches to formalize the neural computations that support decision-making. In contrast to traditional neuroscientific practice, in which individual laboratories each probe different behaviors and record from a few select brain areas, IBL aims to deliver a standardized, high-density approach to behavioral and neural assays. This approach relies on a highly distributed, collaborative network of ∼50 researchers - postdocs, graduate students, and scientific staff - who coordinate the intellectual, administrative, and sociological aspects of the project. In this article, we examine this network, extract some lessons learned, and consider how IBL may represent a template for other team-based approaches in neuroscience, and beyond.Diffusion magnetic resonance imaging (dMRI) provides a noninvasive method for measuring brain tissue microstructure. q-Space deep learning(q-DL) methods have been developed to accurately estimate tissue microstructure from dMRI scans acquired with a reduced number of diffusion gradients. In these methods, deep networks are trained to learn the mapping directly from diffusion signals to tissue microstructure. However, the quality of tissue microstructure estimation can be limited not only by the reduced number of diffusion gradients but also by the low spatial resolution of typical dMRI acquisitions. Therefore, in this work we extend q-DL to super-resolved tissue microstructure estimation and propose super-resolvedq-DL (SR-q-DL), where deep networks are designed to map low-resolution diffusion signals undersampled in the q-space to high-resolution tissue microstructure. Specifically, we use a patch-based strategy, where a deep network takes

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