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https://click4r.com/posts/g/18734612/the-10-most-terrifying-things-about-pragmatic-authenticity-verificatio Pragmatic Free Trial Meta Pragmatic Free Trail Meta is an open data platform that facilitates research into pragmatic trials. It shares clean trial data and ratings using PRECIS-2, allowing for multiple and diverse meta-epidemiological studies to examine the effects of treatment across trials that employ different levels of pragmatism as well as other design features. Background Pragmatic trials are becoming more widely acknowledged as providing evidence from the real world for clinical decision-making. The term "pragmatic" however, is used inconsistently and its definition and evaluation require further clarification. Pragmatic trials are intended to guide clinical practices and policy decisions, not to prove a physiological or clinical hypothesis. A pragmatic trial should aim to be as close as it is to real-world clinical practices which include the recruiting participants, setting, designing, implementation and delivery of interventions, determination and analysis outcomes, and primary analyses. This is a significant difference between explanatory trials, as defined by Schwartz & Lellouch1 that are designed to confirm a hypothesis in a more thorough way. Trials that are truly practical should avoid attempting to blind participants or clinicians, as this may cause bias in estimates of treatment effects. Practical trials should also aim to attract patients from a variety of health care settings, to ensure that the results can be applied to the real world. Finally the focus of pragmatic trials should be on outcomes that are crucial to patients, like quality of life or functional recovery. This is especially important when it comes to trials that involve the use of invasive procedures or potential dangerous adverse events. The CRASH trial29 compared a 2 page report with an electronic monitoring system for patients in hospitals with chronic heart failure. The tr

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