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https://www.selleckchem.com/products/wh-4-023.html Neurofibromatosis type 1 (NF1) is an autosomal dominant neurocutaneous disease which confers an increased risk of malignant tumour development. Relapsing remitting multiple sclerosis (RRMS) is an inflammatory demyelinating disease of the central nervous system. The coexistence of multiple sclerosis and NF1 is rare but has been reported. Here, we describe the case of a 31-year-old man with NF1 and subacute walking problems with proximal pain in the lower limbs who was successfully treated with natalizumab. The coexistence of multiple sclerosis (MS) and neurofibromatosis type 1 (NF1) is very rare but has been described in the literature.Follow-up of patients with NF1 is important as the early detection and management of MS can prevent further disability.Appropriate treatment and physical therapy can improve the patient's activity and social life. The coexistence of multiple sclerosis (MS) and neurofibromatosis type 1 (NF1) is very rare but has been described in the literature.Follow-up of patients with NF1 is important as the early detection and management of MS can prevent further disability.Appropriate treatment and physical therapy can improve the patient's activity and social life.The authors describe the case of a patient with primary monophasic pulmonary synovial sarcoma presenting as a right pleural effusion, and discuss the underlying diagnostic challenges. There has been tremendous progress in the diagnosis and management of malignant effusion, with thoracoscopic biopsy of the pleura providing the highest diagnostic yield.Even though advanced techniques such as image-guided biopsy and pleuroscopy have relatively high sensitivity and specificity, in rare cases, the diagnosis can still be missed.In clinical practice, all such techniques should be considered in order to achieve an early diagnosis and a better outcome. There has been tremendous progress in the diagnosis and management of malignant effusion, with

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