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https://www.selleckchem.com/products/v-9302.html Conclusions Acupuncture is more than a placebo for chronic pain, and both specific and nonspecific effects can be distinguished in a meta-analysis of appropriate size.Objective Epigenetics, including DNA methylation, histone modification, and posttranscriptional regulation of microRNAs, is the study of heritable changes in gene expression that do not include DNA-sequence alterations. Epigenetics has become a new strategy for basic and clinical research on acupuncture in the last decade. The aim of this research update was to summarize the epigenetic mechanisms of angiogenesis induced by acupuncture treatment in ischemic heart diseases. Materials and Methods The current authors' group has been working to illustrate the mechanism of acupuncture from an epigenetics perspective, which has shed new lights on the mechanisms and applications of acupuncture in cardiovascular diseases. This article summarizes the group's new findings in animal models as well as in patients with chronic stable angina. Progress since 2011 in other teams' research in this field is also discussed in this article. Conclusions Acupuncture could regulate histone modifications and could rescue patients who sustain ischemic injuries. This treatment could possibly work through promoting angiogenesis.Introduction Developing a new and innovative acupuncture technique to deal with acute and chronic pain is a considerable undertaking in itself as many barriers must be overcome. Designing the technique and gaining acceptance is even more daunting and challenging across a large system of medical facilities such as the Department of Defense and the Veterans Administration. Such was the case of Battlefield Acupuncture (BFA), a 5-needle placement in each external ear into specific auricular points to treat acute and chronic pain. Discussion This technique geared for military deployment is rapid, safe, and easily reproducible without side effects because it uses

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