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https://www.selleckchem.com/products/azd9291.html Can improving access to mobile extension improve agricultural productivity? Recent evidence suggests both significant and insignificant ways in which SMS-based agricultural information could affect farming outcomes. It is unclear if variations in the programs' design or the methodological challenges in evaluating the programs cause wide-ranging impacts. Extension hotline services provide rapid, unambiguous information by agricultural experts over the phone, tailored to time- and crop-specific shocks. Using methods from experimental economics, we randomly distributed the hotline number to generate exogenous variation in the access to farming information. We conducted our study among 300 farmers in the South Indian state of Karnataka. Our results show that eliminating informational inefficiencies increases farmers' average yields for a high-stakes pigeon pea crop that faced adverse aggregate shock. The impact on the yield is through the adoption of cost-effective and improved farming practices. However, we do not observe any effect on the crops that were not affected by the shock. Our findings reveal that advisory recommendations customized to time- and crop-specific shocks are associated with a greater impact on agricultural productivity.A single insulin receptor (InR) gene has been identified and extensively studied in model species ranging from nematodes to mice. However, most insects possess additional copies of InR, yet the functional significance, if any, of alternate InRs is unknown. Here, we used the wing-dimorphic brown planthopper (BPH) as a model system to query the role of a second InR copy in insects. NlInR2 resembled the BPH InR homologue (NlInR1) in terms of nymph development and reproduction, but revealed distinct regulatory roles in fuel metabolism, lifespan, and starvation tolerance. Unlike a lethal phenotype derived from NlInR1 null, homozygous NlInR2 null mutants were viable and accelerated DNA repl

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