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https://www.selleckchem.com/CDK.html . Registered at clinicaltrials.gov with study number NCT03426787. Registered at clinicaltrials.gov with study number NCT03426787. Acute kidney injury (AKI) contributes to and complicates chronic kidney disease (CKD). We describe AKI documented in hospital encounters in patients with CKD from the CKD Queensland registry. A retrospective cohort study during 2011 to2016. Participants had been admitted to a hospital in Queensland. AKI was identified from codes. All-cause mortality with or without kidney replacement therapy (KRT), start-up KRT and maintenance KRT, costs of care. Time to outcomes for those with versus without AKI was evaluated using Cox regression models. Mann-Whitney test was used to compare number of admissions, hospitalized days and costs by AKI status. Among 6,365 patients followed up for up to 5.4 years, 2,199 (35%) had 4,711 hospital encounters with an AKI diagnosis. Those with AKI were older (68 vs 64 years old), were more often men (36.7% vs 32.2%; < 0.001), had more advanced CKD stages (stage 3b, 34%; stage 4, 35%; and stage 5, 10%), had more admissions (12 vs 5; < 0.001), and stayed in thengly increased deaths, increased rates of KRT, and higher hospital costs. AKI is associated with strikingly increased deaths, increased rates of KRT, and higher hospital costs. Despite extensive research on health care access for individuals with chronic kidney disease (CKD), there is little research on the relationship between health care access barriers and psychological distress. An observational study based on the publicly available 2013 to 2017 US National Health Interview Survey data. 3,923 respondents 18 years or older who self-reported a diagnosis of CKD in the preceding 12 months. Psychological distress was measured using the Kessler Psychological Distress Scale (K6). Barriers to health care access included lack of health insurance coverage, lack of a usual source of health care, and financial barriers to accessing/

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