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https://www.selleckchem.com/products/dasa-58.html 6, 22.2 and 25.8 months, respectively. Anemia, lymphopenia, and neutropenia were the most common adverse events. NDLS treatment was overall well-tolerated without any new safety concerns. Biweekly NDLS for >20 cycles was effective and well-tolerated in patients with mCRPC. NDLS can potentially be used for long-term management, which may be a requirement for most patients with mCRPC. 20 cycles was effective and well-tolerated in patients with mCRPC. NDLS can potentially be used for long-term management, which may be a requirement for most patients with mCRPC.Background In healthcare, employees are exposed to continuous change when new methods are implemented to optimize care. Such changes may result in qualitative job insecurity (QJI), i.e., a fear concerning the potential loss of important job features. QJI is an individual experience; however, it may be shared within a team to a varying extent. This study examines how QJI perceptual (in)congruence between individuals and their teammates relates to individuals' well-being. Method Healthcare employees (N = 305) from 30 healthcare units completed questionnaires measuring QJI, work engagement, and recovery. Results Multi-level polynomial regression analyses showed that QJI congruence had a curvilinear relationship with well-being employees reported higher work engagement when QJI perceptions were in agreement, both when QJI was low and high. We observed a negative relationship between QJI congruence and recovery. Recovery was lower when perceptions of QJI were in agreement and were high (vs. low). Finally, we found support for the effects of perceptual incongruence when employees reported higher QJI than their teammates, they experienced lower recovery and engagement. Conclusions To understand how employees' QJI relates to their well-being, it is essential to consider their teammates' perceptions. The social context can augment or reduce individuals' stress reactions to

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