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https://www.selleckchem.com/products/ubcs039.html The NiMn2O4/C necklace-like microspheres (NLM) were successfully prepared by hydrothermal method and oil bath. This unique necklace-like structure makes them exhibit the enhanced intrinsic oxidase-like activity, as the special interface can help capture electrons from 3,3',5,5'-tetramethylbenzidine. The fabricated NiMn2O4/C NLM were successfully used as the high-performance oxidase mimetic to catalyze the oxidation of TMB directly for the color reaction. A simple colorimetric method for detection of ascorbic acid by fading was developed, and the high sensitivity with the low detection limit (0.047 μM) was achieved. It is a facile route to fabricate the NiMn2O4/C NLM as the high-performance oxidase mimetic for colorimetric biosensing.Aggregation-induced emission luminogens (AIEgens) have been widely used to design fluorescent probes for chemosensing and bioimaging. However, it is still challenging to design long-lived AIE-active probes due to the lack of aggregation-induced phosphorescence (AIP) luminogens. In this work, we design and synthesize a long-lived molecular probe with aggregation-induced phosphorescence property for aluminum ion-specific detection by introducing multiple carboxylic acid groups in a unique twisted molecular skeleton, and develop a first phosphorescent detection method for aluminum ion based on aggregation-induced emission mechanism. The introduction of six carboxylic acid groups into the probe not only significantly enhances the water-solubility but also provides specific recognition unit for aluminum ions via complexation. The probe shows a very sharp emission enhancement in the presence of aluminum ions via aluminum ion-triggered aggregation-induced emission. The cytotoxicity test of the probe shows its biocompatible nature, and further imaging results in live human cells and roots of live Arabidopsis thaliana demonstrates that the designed AIP-active probe is capable of monitoring aluminu

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