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https://www.selleckchem.com/products/esi-09.html The time trend for 0-30 days was only upward in the North and Northeast, with APCs of 29.75% and 20.56%, respectively. In conclusion, since 2018 there were more cases that initiated oral cancer treatment within the stipulated timeframe, as provided in Law n. 12,732/2012 (up to 60 days), with regional differences and a stationary trend in most regions and in Brazil as a whole. Partial achievement of the target, the predominance of a stationary trend, and regional inequalities indicate the need to continue monitoring time-to-treatment for oral cancer in Brazil and to intensify efforts to guarantee timely healthcare.Misoprostol is a medicine with a "double" social life recorded in several places, including Brazil. Within formal and authorized health facilities, it is an essential medicine, used for life-saving obstetric procedures. On the streets, or in online informal markets, misoprostol is treated as a dangerous drug used to induce illegal abortions. In the Brazilian case, despite a rich anthropological and public health analysis of the social consequences of misoprostol's double life, there are no studies on the legal implications. This article offers such descriptive analysis, presenting and examining a comprehensive dataset of how Brazilian courts have treated misoprostol in the past three decades. It consists of an encompassing mapping of the "when, where, how, and who" of misoprostol criminalization in Brazil, pointing to the unjust consequences of the use of criminal law for the purpose of protecting public health.Infodemiology has been widely used to assess epidemics. In light of the recent pandemic, we use Google Search data to explore online interest about COVID-19 and related topics in 20 countries of Latin America and the Caribbean. Data from Google Trends from December 12, 2019, to April 25, 2020, regarding COVID-19 and other related topics were retrieved and correlated with official data on COVID-19 cases

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