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https://www.selleckchem.com/products/purmorphamine.html On MeRIP-Seq data of 69,446 methylation sites under 32 experimental conditions from 10 human cell lines, BDBB unveiled two LCPs, and Gene Ontology (GO) enrichment analysis showed that they were enriched in histone modification and embryo development, etc. important biological processes respectively. The GOE_Score scoring indicated that the biclustering results of BDBB in the m6A epi-transcriptome data are more biologically meaningful than the results of other biclustering algorithms.We propose a novel structured analysis-synthesis dictionary pair learning method for efficient representation and image classification, referred to as relaxed block-diagonal dictionary pair learning with a locality constraint (RBD-DPL). RBD-DPL aims to learn relaxed block-diagonal representations of the input data to enhance the discriminability of both analysis and synthesis dictionaries by dynamically optimizing the block-diagonal components of representation, while the off-block-diagonal counterparts are set to zero. In this way, the learned synthesis subdictionary is allowed to be more flexible in reconstructing the samples from the same class, and the analysis dictionary effectively transforms the original samples into a relaxed coefficient subspace, which is closely associated with the label information. Besides, we incorporate a locality-constraint term as a complement of the relaxation learning to enhance the locality of the analytical encoding so that the learned representation exhibits high intraclass similarity. A linear classifier is trained in the learned relaxed representation space for consistent classification. RBD-DPL is computationally efficient because it avoids both the use of class-specific complementary data matrices to learn discriminative analysis dictionary, as well as the time-consuming l₁/l₀-norm sparse reconstruction process. The experimental results demonstrate that our RBD-DPL achieves at least comparab

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