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https://www.selleckchem.com/products/dtag-13.html Biomarker studies are needed to test the hypothesis that resilience of the elderly during a pandemic can be improved by countering chronic inflammation and/or removing senescent cells. Our review suggests that more samples should be taken and saved systematically, following minimum standards, and data be made available, to maximize healthspan & minimize frailty, leading to savings in health care, gains in quality of life, and preparing us better for the next pandemic, all at the same time.Background While endoscopy is recommended at one year after colorectal cancer (CRC) resection to detect locally recurrent CRC, prior work at our Veterans Affairs (VA) facility demonstrated that 35% of patients achieve this metric. Study design The interdisciplinary team used quality improvement methods to standardize processes and implement a gastroenterology-managed virtual surveillance clinic. The intervention clinic was implemented in August 2014. Veterans who underwent resection for stage I-III CRC at a single VA facility from January 2010 - December 2017 were included, with those undergoing resection between January 2010 - July 2014 considered pre-intervention and those undergoing resection between August 2014 - December 2017 considered post-intervention. The primary outcome was the proportion of eligible patients for whom endoscopy was completed within 1 year of resection. Secondary outcomes were the proportion who completed endoscopy within 18 months of resection or at any time post-resection, and time to surveillance endoscopy. Results A total of 186 patients underwent resection for stage I-III CRC from 2010-2017; of these 160 (86%) were eligible for endoscopy at 1-year post-resection (98 pre-intervention and 62 post-intervention). In the pre-intervention period, 30/98 (30.6%) underwent surveillance endoscopy within one year versus 31/62 (50.0%) post-intervention (P=0.031). When evaluated at 18 months after resection, 56/98

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