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https://www.selleckchem.com/products/r-gne-140.html ating initial carious lesions on occlusal fissures, offering the advantages of better resin penetration and retention. To determine the effect of two adhesive systems and a glass ionomer coating resin on fluoride release and concurrent pH changes over a period of 168 days. Four restorative materials were investigated a giomer Beautiful II, an "alkasite" material Cention, a conventional composite Filtek Z250, and a glass ionomer cement Fuji IX Extra. Light-cured composite specimens were coated using G-aenial Bond and Clearfil Universal Bond Quick. Glass ionomer specimens were coated using GC Fuji Coat LC. Uncoated specimens were used as references. Quantitative fluoride release and pH changes were measured after1 h, 24 h, 2 days, 7 days, 28 days, 84 days, and 168 days. The cumulative fluoride release after 168 days increased for uncoated specimens in the following order Filtek Z250 < Beautifil II < Cention < Fuji IX Extra. A comparatively lower fluoride release was measured for the composites coated with Clearfil Universal Bond Quick, with cumulative values after 168 days increasing in the following order Filtek Z250 < Beautifil II < Cention. The composites coated with G-aenial Bond showed lower fluoride release compared to the uncoated specimens, with cumulative values increasing in the following order Filtek Z250 < Beautifil II < Cention. The composites coated with G-aenial Bond showed pH values in the acidic range (4.4-5.7) after 1 h and 24 h. Fluoride release varied among the investigated restorative materials and depended on the use of dental adhesives and coatings. The pH of all materials, coating types and time points varied. Fluoride release varied among the investigated restorative materials and depended on the use of dental adhesives and coatings. The pH of all materials, coating types and time points varied. The purpose of this study was to evaluate shade matching ability of dental professionals and stude

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