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https://www.selleckchem.com/products/z-vad(oh)-fmk.html 098 ± 0.021 μM) with similar biological activity to artemether. The molecule 13 is a typical drug repurposing case due to previous other approved therapeutic uses on Chinese medicine as a non-specific cholinergic antagonist, thus it could be accelerated the drug development process. Additionally, molecular dynamics studies were used to confirm stability of the molecular interactions identified by molecular docking. Thus, representative structures of P. falciparum ENR can be used in a study to propose new derivatives for evaluation of biological activity in vitro and in vivo. Communicated by Ramaswamy H. Sarma.This study explored the factors associated with the engagement of women in intimate partner homicide (IPH) through 10 in-depth interviews with women incarcerated in three correction facilities in Oromiya Regional State of Ethiopia. In addition, key informant interviews and six focus groups involving traditional leaders, Kebele administrators, and community members help triangulate the findings. The study revealed insight into women's social, psychological, and economic status prior to their crime. Low levels of education and economic opportunity, forced marriage, marital dispute due to polygamy, spousal violence, and low levels of community support were associated with IPH. Implications for research, policy, and practice are discussed.Cervical cancer is the fourth most common cancer among women globally, with approximately 580,000 new diagnoses in 2018. Approximately, 90% of deaths from this disease occur in low- and middle-income countries, especially in areas of high HIV prevalence, and largely due to limited prevention and screening opportunities and scarce treatment options. In this overview, we describe the opportunities and challenges faced in many low- and middle-income countries in delivery of cervical cancer detection, treatment and complete pathways of care. In particular, drawing on our experien

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