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https://www.selleckchem.com/products/gsk2606414.html Background Health locus of control (LOC) represents an individual's beliefs regarding one's ability to influence health outcomes. In patients with chronic and neurodegenerative diseases, greater internal LOC has been associated with lower levels of disability. Objective To examine LOC in patients with Huntington disease (HD). Methods A cross-sectional study of individuals affected by HD, stratified by disease status, was conducted. Participants completed a demographic questionnaire, the Internal Control Index (ICI), and the Hospital Anxiety and Depression Scales. Results Thirty-four subjects completed the study. All groups demonstrated greater internal LOC (measured by ICI scores), and significant differences between groups were observed. Secondary analysis demonstrated relationships between depressive symptoms and anxiety symptoms, and ICI score and time from clinical diagnosis of HD. Conclusion As patients with chronic pain and neurodegenerative diseases such as HD are likely to present for chiropractic care, identifying factors such as anxiety, depression and LOC may affect patients' response to care.Background Staying Well, Independent and Fit Together (SWIFT), a seniors' exercise program, aims to promote health, strength, mobility and community engagement. We compared quality of life and balance confidence in SWIFT participants and non-participants, aged 60 years and older. Methods Cross-sectional study comparing participants and non-participants in SWIFT program using Older People's Quality of Life Questionnaire (OPQOL) and Activities-specific Balance Confidence Scale (ABCS). Results Seventy participants completed surveys, 41 in experimental and 29 in control group. We found a statistically significant between group difference favoring the control group in overall OPQOL score but not in OPQOL subscale nor overall ABCS scores. Participants in both groups participating in weekly exercises had non-significantly

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