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https://www.selleckchem.com/products/iwp-4.html RESULTS Our in vivo results confirmed the predicted 1/b power law for PTE. Moreover, our analysis showed that using an axisymmetric b-tensor a power-law only exists under very specific conditions (a) "stick-like" tissue geometry and purely LTE or purely PTE waveforms; and (b) "pancake-like" tissue geometry and a purely LTE waveform. CONCLUSIONS A complete analysis of the power-law dependencies of the diffusion-weighted signal at high b-values has been performed. Only three specific forms of encoding result in a power-law dependency, pure linear and pure PTE when the tissue geometry is "stick-like" and pure LTE when the tissue geometry is "pancake-like". The different exponents of these encodings could be used to provide independent validation of the presence of different tissue geometries in vivo. © 2020 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.OBJECTIVES The use of patient-reported outcome (PRO) measured outside clinical trials is not well defined. We report the first analysis of the prospective PRO study within the Swedish acute myeloid leukemia (AML) and the acute lymphoblastic leukemia (ALL) registries. METHODS PRO was requested 6 months after diagnosis. The EORTC Quality of life Questionnaire Core 30-item, the Patient Health Questionnaire-8 (PHQ-8), and questions from a Swedish National Cancer Questionnaire were used. RESULTS An invitation letter was sent to 398 patients; 255 (64%) responded, 60% web-based, and 40% on paper. The ALL cohort had lower physical, role and social functioning, higher symptom burden, and more financial difficulties compared to the AML cohort. A PHQ-8 score ≥ 10p, which indicates depression, was reported in 18% of the patients; 33% of these patients reported being prescribed antidepressants. The patients' overall experience of care was satisfying, but more psychological and practi

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