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https://www.selleckchem.com/products/bv-6.html 013), and postoperative chemotherapy (p = 0.006) as independent prognostic factors. In the H-group, patients who received chemotherapy had a better prognosis than those who did not (p = 0.001). Postoperative chemotherapy is beneficial in colorectal cancer patients with more than two of the following factors age ≥ 70, carbohydrate antigen 19-9-positivity, pT4, and lymph node metastasis. Postoperative chemotherapy is beneficial in colorectal cancer patients with more than two of the following factors age ≥ 70, carbohydrate antigen 19-9-positivity, pT4, and lymph node metastasis. Cardiac rehabilitation (CR) referral is a Class I post-myocardial infarction (MI) recommendation from the American Heart Association and the American College of Cardiology, yet referral rates remain strikingly low, with cardiologists some of the worst under-referring offenders. This paper seeks to review the evolution of CR and its well-established benefits, as well as reasons behind the poor referral and utilization. CR is a secondary prevention program for cardiovascular disease (CVD) that was first initiated in the 1970s as a hospital-based exercise program after an acute MI, but then evolved into a comprehensive multi-disciplinary program for patients with a wider range of cardiovascular diseases. CR mortality and morbidity benefits have endured over decades, even as interventional and pharmacological cardiovascular therapeutics have improved and as patients have become relatively more stable. Despite being an evidence-based clinical standard, referral and participation in CR are disconcertingly low. morbidity benefits have endured over decades, even as interventional and pharmacological cardiovascular therapeutics have improved and as patients have become relatively more stable. Despite being an evidence-based clinical standard, referral and participation in CR are disconcertingly low. In efforts to combat poor referral rates, and improve car

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