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https://www.selleckchem.com/ BACKGROUND Chronic kidney disease (CKD) is a largely asymptomatic condition of diminished renal function, which may not be detected until advanced stages without screening. AIM To establish undiagnosed and overall CKD prevalence using a cross-sectional analysis. DESIGN AND SETTING Longitudinal cohort study in UK primary care. METHOD Participants aged ≥60 years were invited to attend CKD screening visits to determine whether they had reduced renal function (estimated glomerular filtration rate [eGFR] 60 years. Follow-up will provide data on annual incidence, rate of CKD progression, determinants of rapid progression, and predictors of cardiovascular events. ©The Authors.BACKGROUND Urinary tract infections (UTIs) are one of the most common bacterial infections managed in general practice. Many women with symptoms of uncomplicated UTI may not benefit meaningfully from antibiotic treatment, but the evidence base is complex and there is no suitable shared decision-making resource to guide antibiotic treatment and symptomatic care for use in general practice consultations. AIM To develop an evidence-based, shared decision-making intervention leaflet to optimise management of uncomplicated UTI for women aged less then 65 years in the primary care setting. DESIGN AND SETTING Qualitative telephone interviews with GPs and patient focus group interviews. METHOD In-depth interviews were conducted to explore how consultation discussions around diagnosis, antibiotic use, self-care, safety netting, and prevention of UTI could be improved. Interview schedules were based on the Theoretical Domains Framework. RESULTS Barriers to an effective joint consultation and appropriate prescribing included lack of GP time, misunderstanding of depth of knowledge and miscommunication between the patient and the GP, nature of the consults (such as telephone consultations), and a history of previous antibiotic therapy. CONCLUSION Consultation time pressures combined wi

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