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https://www.selleckchem.com/products/ml349.html Background Transverse-plane kinematic deviations of lower limbs are common in children with unilateral cerebral palsy (UCP), often with detrimental consequences for gait. Research question To identify the most important factor among rotational anomalies of lower limbs for gait in children with UCP. Methods In a descriptive observational study, 42 children with UCP (age; 5-8 years) who had the ability of independent walking were included. Comprehensive gait analysis was performed and included assessment of the transverse-plane kinematic deviations of the lower limbs [pelvis, hip, and ankle rotation angles, and foot progression (FP) angle], and spatial-temporal gait features [velocity, step length (SL), single-limb support time (SLSt), temporal gait-symmetry index (T-GSI), and spatial gait-symmetry index (S-GSI)]. Results and significance The regression analysis indicated that hip rotation was the key determinant of gait velocity (R2 = 0.75, P less then .001) and S-GSI (R2 = 0.24, P = .001). The FP angle was the most important factor for T-GSI (R2 = 0.22, P = .002). The ankle rotation explained in part the variance in T-GSI (R2 = 0.10, P = .001). Conclusion Gait velocity and spatial gait-symmetry are primarily affected by hip rotation anomalies. The temporal gait-symmetry is generally associated with the FP angle deviation and partly with ankle rotation deviation.Backgound Dynamic valgus has been the focus of many studies to identify its association to an increased risk of running-related injuries. However, it is not known which physical and biomechanical variables are associated with this movement dysfunction. Research question This study aimed to test the correlation between strength, flexibility and biomechanical variables and dynamic valgus in female runners. Methods Twenty-nine healthy females ran on a treadmill at 2.92 m/s and performed strength, range of motion and endurance tests. Pelvic, hip and ankle kinematics

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